Supercritical Fluid Chromatography

Supercritical Fluid Chromatography

Supercritical fluid chromatography is a type of normal-phase chromatography in which the mobile phase is a supercritical fluid, having the properties of both a gas and a liquid. Supercritical Fluid Chromatography

SFC is often used for chiral separations, but the growing range of stationary phases available is extending its reach to achiral separations, for both sample prep and analysis.

A typical SFC system includes a CO2 pump, injector, oven, column, detector, and recorder. Since the chromatographic flow path must be pressurized, a backpressure regulator is also required.

What Are Applications for Supercritical Fluid Chromatography?

SFC can be used to analyze many materials, including:

  • Drugs
  • Foods
  • Pesticides and herbicides
  • Polymers
  • Surfactants
  • Fossil fuels
  • Explosives
  • And more!

Systems are available that feature easy switching for use with HPLC applications.

Supercritical Fluid Extraction System Supercritical Fluid Chromatography Extraction (SFE) System 1260 Infinity Analytical SFC System Preparative Supercritical Fluid Chromatography (SFC) System

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