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So far Cal-L Enterprises has created 58 blog entries.

FDA Revises Guidance on Safety Testing of Drug Metabolites

The US Food and Drug Administration (FDA) on Tuesday released revised guidance on recommendations to industry on when and how to identify and characterize drug metabolites whose nonclinical toxicity needs to be evaluated. The revisions mean the new guidance supersedes guidance from February 2008. The guidance has been revised to be in alignment with ICH [Read More...]

Honeywell Establishes Research Chemicals Business

Honeywell announced the establishment of a new chemicals business on Monday that aims to strengthen product partnerships with researchers. The new unit, Honeywell Research Chemicals, will operate under the company’s Fine Chemicals business and help provide a supply of reagents and solvents for the analytical testing, drug discovery, and applied materials sectors. “Our customers are [Read More...]

Are Sweeteners as Natural as We Think? – Chromatography Investigates

A team from the University of Bonn in Germany has found that compounds known as steviol glycosides are unchanged during different stages of production. The report helps to confirm that the sweetener or sugar substitute known as stevia can be considered as a natural sweetener. Scientists analysed three different batches of stevia throughout the production [Read More...]

FDA’s Glyphosate Testing on Hold

Back in February of this year, FDA announced that it would begin testing foods for glyphosate residues. By way of background, glyphosate is the active ingredient in popular garden weed killers and is reported to be the most-used agricultural chemical in the world. Some environmental groups have called for a ban on the use of this substance in agriculture.  The International [Read More...]

Whisky all go go: Cheminformatic botanic

Water of life Cheminformatics can be used to process data from headspace mass-spectrometry (HS-MS), mid-infrared (MIR) and UV–Vis spectroscopy and so ascertain the authenticity and origin of Irish, Spanish, Bourbon, Tennessee Whisky and Scotch, according to a study published by researchers from Poland and Spain. Their approach is quick and simple and requires no pre-preparation [Read More...]

Proficiency Analytical Testing overhauled by USAFSAM experts

WRIGHT-PATTERSON AIR FORCE BASE, Ohio -- In the past two years, the United States Air Force School of Aerospace Medicine -- part of the Air Force Research Laboratory’s 711th Human Performance Wing -- has overhauled the bioenvironmental engineering Proficiency Analytical Testing Program, resulting in a program capable of meeting the operational needs of the warfighter [Read More...]

Ripple effect: The Red River, what’s in the water and how safe is it?

WINNIPEG — Long before Winnipeg had ever been incorporated as a city, its largest river defined and shaped the landscape. The Red River has, for generations, been at the cultural and economic heart of Winnipeg. Archaeological evidence of human life, dating back over 6,000 years has been found on the riverbanks. It played a vital role for Manitoba’s [Read More...]

Relevance Of Microbial Finished Product Testing In Food Safety Management

Abstract Management of microbiological food safety is largely based on good design of processes, products and procedures. Finished product testing may be considered as a control measure at the end of the production process. However, testing gives only very limited information on the safety status of a food. If a hazardous organism is found it [Read More...]

Internal Standards– Turning Good Data Into Great Data

Everyone likes to have a safety net, and scientists are no different. This month I will be discussing internal standards and how we can use them not only to improve the quality of our data, but also give us some ‘wiggle room’ when it comes to variation in sample preparation. Internal standards are widely used [Read More...]

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