In states where cannabis is legalized, some analytical laboratories are tasked with identifying and quantifying pesticide content in plant material. This is a relatively new concept in the study of cannabis as most forensic laboratories that work with seized plant material are only concerned with positively identifying the sample as cannabis. Laboratories of this nature, often [Read More...]
Study finds that GC-MS changes or destroys sample compounds DEGRADING EXPERIENCE LC-MS peaks from analyses of a small-molecule sample maintained at room temperature (bottom) and heated for five minutes at 250 °C (top) differ considerably. If you’ve used gas chromatography-mass spectrometry (GC-MS) to analyze unknown compounds from cells and biological tissue, a new [Read More...]
Identification of suspect substances depends on reference materials that are in short supply. Attempts to understand and control new synthetic recreational drugs are being hindered by analysis laboratories' inability to obtain pure samples of the compounds, experts say. The growing problem of synthetic drugs — which include mimics of cannabis and amphetamine — came [Read More...]
A new universal petrochemical analyzer combines the speed of ballistic gas chromatography (GC) with the ability of high-pressure mass spectrometry (HPMS) technology to identity molecules at lower limits. Officials with Boston-based 908 Devices Inc. are seeking to “democratize” chemical analysis with mass spectrometry by freeing it from its Achilles heel, the complex vacuum pumping system. [Read More...]
The determination of water content in solvents, alcoholic beverages and various consumer products such as foods, pharmaceuticals, fuels, and petroleum products is one of the most common types of chemical testing. Many techniques such as gravimetric analysis, Karl Fischer Titration, near infra-red spectroscopy, gas chromatography (GC) and others have been used for water quantification with [Read More...]
Introduction Nowadays, the cultivation of grapes is widely spread around the world with an estimated surface area of 7.6 million of hectares in 2014 [1]. Grape production is an important activity due to the high nutritional properties of grapes and their ancient domestication leading to a large variety of by-products [2]. Grapes are consumed both [Read More...]
Multi-Residue Analysis of 90 Emerging Contaminants In Liquid And Solid Environmental Matrices By Ultra-High-Performance Liquid Chromatography Tandem Mass Spectrometry Abstract Reported herein is new analytical methodology for the determination of 90 emerging contaminants (ECs) in liquid environmental matrices (crude wastewater, final effluent and river water). The application of a novel buffer, ammonium fluoride improved [Read More...]
Analytical laboratories in the pharmaceutical industry may serve many masters: manufacturing operations needs to release product quickly; quality assurance protects patients; product development requires analyses to support understanding of product stability, delivery systems and other factors. A contract analytical laboratory that works with many pharmaceutical companies, McCrone Associates (Westmont, Ill.) has used Raman microspectroscopy to solve [Read More...]
Before analytical results can be generated, a laboratory requires a suitable calibrated instrument, a trained analyst, an approved/validated method, appropriate reference materials, a standard operating procedure to help ensure the instrument is used in a consistent and reproducible manner and samples to test. When considered from a “compliance principles” perspective, these points are essential to [Read More...]
Most laboratories that use gas chromatography (GC), have at least one GC hyphenated with a mass spectrometer (GC-MS) these days. GC-MS has added advantages over GC detectors in that it provides a third dimension of data in the form of a mass spectrum. The sum of the abundance of all ions at each scan number [Read More...]
