Advanced Instruments Model 20G High Throughput Multi-Sample
Osmometer with 2 axis Robot;

Advanced® Model 20G High Throughput Multi-Sample Osmometer

Advanced® Model 20G High Throughput Multi-Sample Osmometer

Advanced® Model 20G Osmometer High-Throughput Multi-Sample Osmometer
for Osmolality Measurement
The Advanced Instruments Osmometer, Model 20G is specifically designed to support scale-down, high-throughput, cell-culture process development. The 20G Osmometer is capable of measuring the osmolality of 96 samples in 35 minutes using freezing point depression (FPD) technology.
With culture media containing upwards of 100 compounds at varying concentrations, precisely measuring osmolality  is more important than ever. Osmolality information is a key parameter due to its relationship between cells and media.
The ability to accurately monitor nutrient depletion and the build up of toxic waste products is key for identifying ideal conditions for cell growth. The 20G can process far more samples in far less time!
The system is ideal for:
  • Suspension mammalian cell cultures
  • Plant cell cultures
  • Bacterial fermentation
  • Areas where osmolality of media can be critical to success include:
  • Clone screening
  • Media development
  • Process parameter optimization studies
The 20G Osmometer includes:
  • 20 µL Sample Size – Ideal for scale-down reactor vessels
  • Color, touch screen monitor provides instrument control, osmometer status, and test results as they occur
  • Clear plastic safety enclosure for visual monitoring, front access opening for sample loading, light-curtain protected access point with emergency stop for safety
  • Bar-Coded Sample Tube Rack – for positive sample identification
  • High-Throughput Analytics – Far more samples in far less time!
Advanced® Model 20G Osmometer Technical Specifications
Power Requirements: 208 VAC (60 Hz), 3-Phase with neutral and ground, 20A; 115 VAC (60 Hz), 12A
Osmometer Fuses (2): 250V time delay (Type T): 2-Amp
Osmometer Memory Backup: Integral lithium cell; 10-year life (typical); (not user-replaceable)
Computer MemoryBackup: Integral lithium cell (not user-replaceable)
Uninterruptible Power Supply Battery: Sealed, maintenance-free lead acid; 3-5 year life (typical); (not user-replaceable)
Robot Memory Backup: 4 batteries; 1-2 year life (typical); (not user-replaceable)
Robot Controller Memory Backup: 3 batteries; 2-year life (typical); (not user-replaceable)
Pneumatic Air Supply: 3.5 to 10.0 bar (51 to 150 psi)
Sample Volume: 20 μL
Sample Capacity: Up to 96 samples
Units: mOsm/kg H2O
Range: 0 to 2000 mOsm/kg H2O
Resolution: 1 mOsm/kg H2O
Communications: Ethernet, USB, RS-232

Performance at Reference Conditions
Coefficient of Variation: 2.0%
Linearity: ±3 mOsm/kg H2O between 0 and 300 mOsm/kg H2O; than less ±1% between 300 and 850 mOsm/kg H2O; less than 1.5% above 850 mOsm/kg H2O
Repeatability:  0 to 400 mOsm: Standard Deviation less than or equal to 3 mOsm/kg H2O
400 to 2000 mOsm: Standard Deviation less than or equal to 0.75%
Drift: Less than 1 mOsm/kg H2O per month
Performance Over Operating Conditions
Temperature Effects: Less than 1 mOsm/kg H2O for every 5°C (9°F) ambient temperature change
Humidity Effects: 0.12% typical increase in osmolality value per minute during elapsed test cycle at approximately 30% RH
Operating ConditionsPneumatic Pressure: 3.5 to 4.5 bar (51 to 66 psi)
Temperature: 18°C to 35°C (64°F to 95°F)
Humidity: 30 to 80% relative humidity (non-condensing)
Storage Temperature: -40°C to +45°C (-40°F to +113°F)
Osmometer Start-up Time: Immediately from stand-by; under 5 minutes from power-on
Test Time: 90 seconds per sample, typical
Sample Throughput: 96 samples tested in approximately 35 minutes

226 cm x 132 cm x 142 cm
(89″ H x 52″ W x 56″ D)

Net:  557 kg (1225 lbs.) 
Shipping:  955 kg (2100 lbs.)